| evolutionary genetics group | ::: | institute | ::: | university | ::: |  |
| Ryszard Korona ryszard.korona@uj.edu.pl |
Professor Institute of Environmental Sciences Jagiellonian University Gronostajowa 7, 30-387 Kraków, Poland phone + 48 12 664 51 36 fax + 48 12 664 69 12 mobile + 48 510 071 693 |
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Selected publications
Students and collaborators
Research interests:
adaptation and maladaptation, functional genomics, experimental evolution
Yeast, Saccaromyces cerevisiae, a model organism in genetics and genomics
Spontaneous mutations: rate of origin, selective value, domination
Planned gene deletions in the analysis of genetic networks
Molecular mechanisms of phenotypic buffering of genetic damage
Growth, starvation, stress - genetic variation under different conditions
Experimental evolution of laboratory populations of microorganisms
Selected publications
Korona, R. 2011. Gene dispensability. Current Opinion in Biotechnology 22: 547-551. doi: 10.1016/j.copbio.2011.04.017 Epub 2011 May 16.
abstract | PDF
Tomala, K., M. Micinska, U. Paluchniak and R. Korona. 2011. Convergent lifespan reaction norms in the yeast cultures exposed to different environmental stresses. Journal of Evolutionary Biology 24(2):457-61. doi: 10.1111/j.1420-9101.2010.02189.x. Epub 2010 Dec 3.
abstract | PDF
Fudala, A. and R. Korona. 2009. Low frequency of mutations with strongly deleterious but nonlethal fitness effects. Evolution 63(8):2164-71. doi: 10.1111/j.1558-5646.2009.00713.x. Epub 2009 Apr 13.
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Jakubowska, A. and R. Korona. 2009. Lack of evolutionary conservation at positions important for thermal stability in the yeast ODCase protein. Molecular Biology and Evolution 26(7):1431-4. Epub 2009 Apr 6.
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Tomala, K. and R. Korona. 2008. Alleviation of deleterious effects of protein mutation through inactivation of molecular chaperones. Molecular Genetics and Genomics 280: 409-417. doi: 10.1007/s00438-008-0374-x.
abstract
Jasnos, Ł., K. Tomala, D. Paczesniak and R. Korona. 2008. Interactions between stressful environment and gene deletions alleviate the expected average loss of fitness in yeast. Genetics 178: 2105-2111.
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Tomala, K. and R. Korona. 2008. Molecular chaperones and selection against mutations. Biology Direct 3:5, doi:10.1186/1745-6150-3-5.
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Jasnos, Ł. and R. Korona. 2007. Epistatic buffering of fitness loss in yeast double deletion strains. Nature Genetics 39: 550-554.
abstract
Bobula, J., K. Tomala, E. Jez, D. Wloch, R. H. Borts and R. Korona. 2006. Why molecular chaperones buffer mutational damage: A case study with a yeast Hsp40/70 system. Genetics 174: 937-944.
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Śliwa, P. and R. Korona. 2005. Loss of dispensable genes is not adaptive in yeast. Proceedings of National Academy of Sciences USA 102: 17670-17674.
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Jasnos, Ł. P. Sliwa and R. Korona. 2005. Resolution and repeatability of phenotypic assays automated growth curve analysis in yeast and bacteria. Analytical Biochemistry 344: 138-140.
Korona, R. 2004. Experimental studies of mutational load in Saccharomyces cerevisiae. Research in Microbiology 155: 301-310.
abstract
Sliwa, P., J. Kluz and R. Korona. 2004. Mutational load and the transition between diploidy and haploidy in experimental populations of the yeast Saccharomyces cerevisiae. Genetica 121: 285-293.
abstract
Szafraniec, K., D. M. Włoch, P. Sliwa, R. H. Borts and R. Korona. 2003. Small fitness effects and weak genetic interactions between deleterious mutations in heterozygous loci of the yeast Saccharomyces cerevisiae. Genetical Research 82: 19-31.
abstract
Włoch, D. M., K. Szafraniec, R. H. Borts and R. Korona. 2001. Direct estimate of the mutation rate and the distribution of fitness effects in the yeast Saccharomyces cerevisiae. Genetics 159: 441-452.
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Włoch, D. M., R. H. Borts and R. Korona. 2001. Epistatic interactions of spontaneous mutations in haploid strains of the yeast Saccharomyces cerevisiae. Journal of Evolutionary Biology 14: 310-316.
Szafraniec, K., R. H. Borts and R. Korona. 2001. Environmental stress and mutational load in diploid strains of the yeast Saccharomyces cerevisiae. Procedings of the National Academy of Sciences USA 98: 1107-1112.
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Korona, R. 1999. Genetic load of the yeast Saccharomyces cerevisiae under diverse environmental conditions. Evolution 53: 1966-1971.
Korona, R. 1999. Unpredictable fitness transitions between haploid and diploid strains of genetically loaded yeast Saccharomyces cerevisiae. Genetics 151:77-85.
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Nakatsu, C. H., R. Korona, R. E. Lenski, F. J. de Bruijn, T. L. Marsh and L. J. Forney. 1998. Parallel and divergent genotypic evolution in experimental populations of Ralstonia sp. Journal of Bacteriology 180:4325-4331.
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Nakatsu, C. H., R. Korona, et al. 1997. Genetic diversity of 2,4 - dichlorophenoxyacetic acid (2,4-D) catabolic genes. In: T. Horikoshi, M. Fukuda and T. Kudo, eds. Microbial Diversity and Genetics of Biodegradation. Japan Scientific Societies Press, Tokyo. pp. 197-206.
Lenski, R. E., G. J. Velicer and R. Korona. 1997. Experimental studies on the evolution of bacteria that degrade 2,4-dichlorophenoxyacetic acid. In: T. Horikoshi, M. Fukuda and T. Kudo, eds. Microbial Diversity and Genetics of Biodegradation. Japan Scientific Societies Press, Tokyo. pp. 83-95.
Korona, R. 1996. Adaptation to structurally different environments. Proceedings of the Royal Society B 263:1665-1669.
Korona, R. 1996. Genetic divergence and fitness convergence under uniform selection pressure in experimental populations of bacteria. Genetics 143:637-644.
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Korona, R. 1995. Evolution of dispersal: a humble but important example. Trends in Ecology and Evolution 10:53-54.
Korona, R., C. H. Nakatsu, L. J. Forney and R. E. Lenski. 1994. Evidence for multiple adaptive peaks from populations of bacteria evolving in a structured habitat. Proceedings of the National Academy of Sciences USA 91:9037-9041.
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Korona, R. and B. R. Levin. 1993. Phage-mediated selection and the evolution and maintenance of restriction-modification. Evolution 47:556-575.
Korona, R., B. Korona and B. R. Levin. 1993. Sensitivity of naturally occurring coliphages to type I and type II restriction and modification. Journal of General Microbiology 139:1283-1290.
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Korona, R. 1991. Genetic basis of behavioral strategies. Dispersal of female flour beetles Tribolium confusum in a laboratory system. Oikos 62:265-270.
Korona, R. 1991. On the role of age and body size in risky animal contests. Journal of theoretical Biology 152:165-176.
Korona, R. 1990. Travel costs and ideal free distribution of ovipositing female flour beetles, Tribolium confusum. Animal Behaviour 40:186-187.
Korona, R. 1989. Evolutionarily stable strategies in competition for resource intake rate maximization. II. Oviposition behavior in Tribolium confusum. Behavioral Ecology and Sociobiology 25:201-205.
Korona, R. 1989. Evolutionarily stable strategies in competition for resource intake rate maximization. I. The model. Behavioral Ecology and Sociobiology 25:193-199.
Korona, R. 1989. Ideal free distribution of unequal competitors can be determined by the form of competition. Journal of Theoretical Biology 138:347-352.
Korona, R., Łomnicki, A. 1988. Individual differences and survival during competition: a simple theoretical model and empirical evidence for flour beetles Tribolium castaneum (Herbst). Functional Ecology 2:330-334.
Present and former collaborators
Katarzyna Tomala - postdoc
Agata Jakubowska - PhD
Agnieszka Marek - PhD
Elzbieta Pogoda - PhD
Magdalena Pieczynska - PhD
Marcin Plech - PhD
Lukasz Jasnos - PhD (2007)
Piotr Sliwa - PhD (2006)
Dominika M. Wloch-Salamon - PhD (2003)
d e s i g n e d b y P a w e ł K a p u s t a